Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function
J. Clin. Invest. Marco Idzko, et al. 117:464 doi:10.1172/JCI28949 [Go to this article.]

Figure 2
Effect of iloprost treatment on distribution of DCs. Single-cell suspensions from MLNs were stained for DCs (A) or B and T cells (B) and analyzed by flow cytometry. Experiments were set up as in Figure 1. Labels indicate sensitization/treatment/challenge. Data (mean ± SEM) were calculated as absolute number of cells. **P < 0.01; ***P < 0.001. (C) Iloprost inhibited the maturation of lung DCs in vivo. A single-cell suspension was prepared from the lungs, and CD11c⁺MHCII^hi lung DCs were analyzed for their expression of CD40, CD80, CD83, and CD86. Data from 1 representative experiment of 3 is shown.