Bone protection by estrens occurs through non–tissue-selective activation of the androgen receptor
J. Clin. Invest. Sara H. Windahl, et al. 116:2500 doi:10.1172/JCI28809 [Go to this article.]

Figure 4
Estren-α has deleterious effects on the uterus in WT mice. (A) Representative uteri from the mice in Figure 2. (B) Histomorphometric quantification of total uterus, myometrium, and endometrium areas. Estren-α was as uterotrophic as E₂, while PSK3471 induced only very moderate uterotrophic effects. **P < 0.01 versus OVX mice.