Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice
J. Clin. Invest. Manyu Li, et al. 116:2653 doi:10.1172/JCI28462 [
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Figure 1Reduced litter size in
AM+/– matings.
The average number of viable offspring at postnatal day 21 and the average number of embryos at gestational day E14.5 were determined for wild-type matings (white bars) and
AM+/– intercrosses (gray bars). The actual average number is recorded at the top of each bar, while the number at the bottom of the bar represents the number of litters examined for each cross. *
P < 0.01 compared with wild-type crosses.
