Figure 2
Validation of the expression levels of the upregulated chemokines.
MCP-1 (A), GRO-α/KC (B), IP-10 (C), and fractalkine (D) expression levels were measured by QPCR using pooled nonamplified cDNA samples (5 animals per pool; n = 3) at different time points (1, 3, and 9 weeks) and different locations (LSS, control, and OSS regions). *P < 0.05 versus control; #P < 0.05 versus LSS. (E) Placement of a nonconstrictive, control cast that does not alter the laminar shear stress did not induce changes in gene expression.
