Absence of bacterially induced RELMβ reduces injury in the dextran sodium sulfate model of colitis
J. Clin. Invest. Laila D. McVay, et al. 116:2914 doi:10.1172/JCI28121 [
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Figure 3Preservation of colonic crypt cell proliferation, architecture, and goblet cells in RELMβ
–/– mice treated with DSS. RELMβ immunostaining in the colon of wild-type (
A) and RELMβ
–/– mice (
B) (magnification, ×200). (
C–
F) Representative photomicrographs of “Swiss-rolled” colonic tissue obtained after 7 days of 4% DSS administration. H&E-stained sections of wild-type (
C) and RELMβ
–/– colons (
D) (magnification, ×100). Alcian blue–stained sections of wild-type (
E) and RELMβ
–/– colons (
F) (magnification, ×100).