Inhibition of T cell activation and autoimmune diabetes using a B cell surface–linked CTLA-4 agonist
J. Clin. Invest. Brian T. Fife, et al. 116:2252 doi:10.1172/JCI27856 [Go to this article.]

Figure 2
Characterization of T cells and B cells in scαCTLA-4 Tg⁺ mice. Flow cytometric analysis was performed to determine the percentage of CD4⁺ T cells, CD8⁺ T cells, and B220⁺ B cells in the spleen, peripheral lymph nodes, and thymus from FVB and FVB.scαCTLA-4 Tg⁺ mice. The number in each histogram quadrant represents the percentage of total cells. Results shown are representative of 3 independent experiments with ≥ 3 mice per group.