Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria
J. Clin. Invest. Masaru Yoshida, et al. 116:2142 doi:10.1172/JCI27821 [Go to this article.]

Figure 2
IgG transport into the lumen of IFABP-mFcRnTg/mβ2mTg/FcRn^–/– mice. (A) Quantitative PCR of cDNA using PCR primers originating in exon 2 in variety of tissues in IFABP-mFcRnTg/mβ2mTg/FcRn^–/– (Tg/FcRn^–/–) mice. IEC, intestinal epithelial cells. (B) Serum rabbit IgG levels in IFABP-mFcRnTg/mβ2mTg/FcRn^–/– (black bars) and littermate control FcRn^–/– mice (white bars) at 24, 48, and 120 hours after injection of rabbit IgG. (C) Serum rabbit IgG levels in IFABP-mFcRnTg/mβ2mTg/FcRn^–/– mice measured at 12 hours after injection of rabbit IgG (n = 4). (D) Secretory rabbit IgG levels in feces of IFABP-mFcRnTg/mβ2mTg/FcRn^–/– mice measured at 12 hours after injection of rabbit IgG as ng per mg of feces (n = 4). *P < 0.05.