CXCR2 ligands and G-CSF mediate PKCα-induced intraepidermal inflammation
J. Clin. Invest. Christophe Cataisson, et al. 116:2757 doi:10.1172/JCI27514 [
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Figure 9Prominent PKCα expression in the epidermis of psoriatic patients. Frozen sections from normal (
A and
B), nonlesional (
C and
D), and psoriatic (
E and
F) epidermis were stained with monoclonal antibodies to PKCα and detected by immunoperoxidase. Results are typical of samples from 4 patients. Representative example of immunostaining for neutrophils in pustular psoriasis epidermis (
G) and TPA-treated K5-PKCα mouse epidermis (
H). PKCα staining in
G (data not shown) was identical to
E and
F. Scale bars, 50 μm.
