Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation
J. Clin. Invest. 116:10 doi:10.1172/JCI27306 [Go to this article.]

Figure 3
LYVE-1–positive vessels in the human decidua express other markers of lymphatic endothelium.

(A) Adjacent sections were analyzed. In situ hybridization with a CCL21-specific probe (green, left panel) showed that LYVE-1–positive vessels (brown, right panel) in the decidua express this chemokine. (B) Immunostaining of adjacent sections revealed the colocalization of LYVE-1 and integrin α₉β₁. (C) In contrast, a pan-ephrin antibody failed to label decidual lymphatic vessels (arrows), but stained invasive cytotrophoblasts (3). Scale bar: 50 μm.