KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice
J. Clin. Invest. Christopher H. Parsons, et al. 116:1963 doi:10.1172/JCI27249 [
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Figure 4Identification of murine leukocyte subpopulations within NOD/SCID spleens. Splenocyte suspensions from KSHV-infected NOD/SCID mice were incubated with antigen-specific monoclonal antibodies (large panels) or their respective isotype controls (small panels). (
A–
F) Approximately 10,000 total live cells were evaluated for the coexpression of B220, Ly49, CD11b, and CD11c for all 2-way combinations. (
G and
H) In separate experiments gating only on the lymphocyte population, coexpression was observed for Ly49 and IL-2Rβ (
G), but not Ly49 and CD3 (
H).