Cholinergic dysfunction in a mouse model
of Alzheimer disease is reversed
by an anti-Aβ antibody
J. Clin. Invest. Kelly R. Bales, et al. 116:825 doi:10.1172/JCI27120 [
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Figure 4Relative mRNA level of ChT-1 in the hippocampus of young (2 months of age) and old (17 months of age) WT and PDAPP transgenic mice as determined by real-time quantitative PCR amplification.
n = 5 mice per group. **
P < 0.01, *
P < 0.05 versus respective 17-month-old groups.