Strain-dependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II–deficient mice
J. Clin. Invest. Ken-ichi Aihara, et al. 117:1514 doi:10.1172/JCI27095 [
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Figure 3Analysis of
HCII gene transcripts, protein, and plasma activity.
(
A) Conventional RT-PCR analysis of full-length
HCII gene. (
B) Western blot analysis of hepatic HCII protein in
HCII+/+ and
HCII–/– mice. (
C) Northern blot analysis of hepatic HCII mRNA in
HCII+/+ and
HCII+/– mice. (
D) Plasma HCII activity in
HCII+/+ (white bar) and
HCII+/– mice (black bar). Values are expressed as mean ± SEM. **
P < 0.01.
n = 12 in each group for plasma HCII activity.
