HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir
J. Clin. Invest. Tae-Wook Chun, et al. 115:3250 doi:10.1172/JCI26197 [Go to this article.]

Figure 3
Persistence of HIV in resting and activated CD4⁺ T cells of infected individuals receiving effective antiviral therapy for prolonged periods of time. (A) Frequency of FACS-sorted resting and activated CD4⁺ T cells carrying HIV proviral DNA. The median values are shown as black bars. (B) Levels of cell-free virions released by resting and activated CD4⁺ T cells in overnight cultures in the absence of activating stimuli. Cell-free supernatants from each culture harvested after 1 day of culture were subjected to the Amplicor HIV-1 test (detection limit of 50 copies of HIV RNA per ml).