The latency-associated nuclear antigen of Kaposi sarcoma–associated herpesvirus induces B cell hyperplasia and lymphoma
J. Clin. Invest. Farnaz D. Fakhari, et al. 116:735 doi:10.1172/JCI26190 [Go to this article.]

Figure 2
LANA expression in spleens. (A) Immunohistochemistry using a rat mAb against LANA (right panels) or rabbit polyclonal antibody against PCNA (left panels) and visualization with NovaRed (brown) and hematoxylin (blue) counterstain in a transgene-negative and a LANA-positive animal. Arrowhead indicates the localization of LANA-positive cells. Magnification, ×400. (B) Diameter of LANA-positive foci for wild-type and transgenic animals (P ≤ 0.01, n = 11). The box represents the interquartile range, the line within the box indicates the median and whiskers indicate the highest and lowest values.