Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice
J. Clin. Invest. 116:2 doi:10.1172/JCI25243 [Go to this article.]

Figure 3
Weights of adipose tissue and liver from male and female Pomc+^/+, Pomc+^/–, and Pomc^–/– mice with and without pHalEx2* transgene expression.

Adipose depots are the combined renal/visceral, gonadal, and subcutaneous inguinal white fat pads. The box and whisker plots show the 10th, 25th, 50th (median), 75th, and 90th percentiles and individual outlying data points (open circles). Males, age 41 ± 1 weeks (n = 3–10). Females, age 55 ± 1.7 weeks (n = 4–6). *P < 0.05, **P < 0.01, and ***P < 0.0001 compared with Pomc^+/+.