Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle
of insulin-resistant offspring
of type 2 diabetic parents
J. Clin. Invest. Katsutaro Morino, et al. 115:3587 doi:10.1172/JCI25151 [
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Figure 1Results of oral glucose tolerance test. Mean plasma concentrations of glucose (
A) and insulin (
B) before and during a 75-g oral glucose tolerance test in control subjects (
n = 6) and IR offspring (
n = 8).
P = 0.0009 for the comparison of the areas under the curve for insulin concentration of control subjects and IR offspring.
