Role of the forkhead protein FoxO1 in β cell compensation to insulin resistance
J. Clin. Invest. Haruka Okamoto, et al. 116:775 doi:10.1172/JCI24967 [Go to this article.]

Figure 4
Pancreatic histology and morphometry. (A) Insulin immunohistochemistry. (B) Glucagon immunohistochemistry. Magnification, ×10 (top panels); ×40 (bottom panels). (C) Measurements of β cell mass. We determined β cell mass as indicated in Methods, following immunohistochemistry with anti-insulin antiserum. We scored at least 3 animals per genotype and 4 sections per animal spaced 80 μm apart. *P < 0.01 versus WT, 305, and 307.