Ikaros transcription factors: flying between stress and inflammation
J. Clin. Invest. George P. Chrousos, et al. 115:844 doi:10.1172/JCI24886 [Go to this article.]

Figure 1
Organization and mutual interactions of the HPA axis and the immune system. Positive and negative influences inside either system are shown as solid and dashed arrows, respectively. Ikaros is expressed and plays an ontogenetic and functional role in both systems. CVO, circumventricular organs; TLR, Toll-like receptor.