A cancer-specific transcriptional signature in human neoplasia
J. Clin. Invest. Francesco Nicassio, et al. 115:3015 doi:10.1172/JCI24862 [Go to this article.]

Figure 5
Selected class D genes predict disease outcome in breast cancer. Two class D genes (SKIN and Ch-TOG) were used together as a predictor (see Supplemental Methods) of prognostic outcome on 2 independent data sets, one generated in-house (A), another from van’t Veer (42) (B), and finally on 15 randomly selected breast tumor patients analyzed by Q–RT-PCR (C) (see Table 1 for details). Data are shown as the probability of remaining free of metastatic relapse, in a Kaplan-Meier plot, as a function of a favorable (dashed line) or unfavorable (continuous line) signature. See also Supplemental Table 13 for details. (C) Probability of remaining metastasis free is shown in a Kaplan-Meier plot, as a function of the presence of the favorable (dashed line) or unfavorable (continuous line) signature. In A–C, the P values indicated were calculated with the log-rank test.