Immunopathogenesis and therapy of cutaneous T cell lymphoma
J. Clin. Invest. Ellen J. Kim, et al. 115:798 doi:10.1172/JCI24826 [
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Figure 4Consequences of malignant T cell cytokine production. In MF/SS, the malignant T cell (CD4
+/CLA
+/CCR4
+) produces the cytokines IL-4, IL-5, and IL-10 that result in a Th2 predominance and subsequent multiple abnormalities in cellular immunity.