Pertussis toxin inhibits neutrophil recruitment to delay antibody-mediated clearance of Bordetella pertussis
J. Clin. Invest. Girish S. Kirimanjeswara, et al. 115:3594 doi:10.1172/JCI24609 [Go to this article.]

Figure 4
Serum antibodies rapidly clear B. pertussisΔPTx but not B. pertussis. C57BL/6 mice were inoculated with either B. pertussis (B.p) or B. pertussisΔPTx (B.pΔPTx). Subsequently, these mice were adoptively transferred 200 μl of either naive serum (NS) or convalescent-phase serum (IS). Mice were sacrificed on the indicated days, and bacterial numbers in the lungs were determined and expressed as geometric mean ± SEM. Dotted line denotes limit of detection. n = 4 per group. *P < 0.001; **P < 0.05.