Lena J. Heung, Maurizio Del Poeta
J Clin Invest.
2005;
115(3):593–595
doi:10.1172/JCI24508
This article Copyright © 2005, The American Society for Clinical Investigation
Abstract
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T
he DEAD-box RNA helicases are enzymes involved in many critical aspects of RNA metabolism within both eukaryotic and prokaryotic organisms. Several studies have shown that these proteins may have important functions in mediating microbial pathogenesis. A new study in this issue of the JCI identifies the first DEAD-box RNA helicase in the pathogenic fungus Cryptococcus neoformans and proposes novel roles for this family of proteins in the development and progression of cryptococcosis.
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