Deficits in amygdaloid cAMP-responsive element–binding protein signaling play a role in genetic predisposition to anxiety and alcoholism
J. Clin. Invest. Subhash C. Pandey, et al. 115:2762 doi:10.1172/JCI24381 [Go to this article.]

Figure 3
Voluntary ethanol intake and NPY levels in the amygdala of P and NP rats. (A) Low-magnification views of NPY mRNA expression (in situ RT-PCR; upper panels) and NPY gold immunolabeling (lower panels) in the CeA of NP and P rats with or without ethanol exposure. Insets show the immuno-gold particles in a cell body at high magnification (×100). Scale bar: 40 μm. (B) Effects of voluntary ethanol intake on mRNA and protein levels of NPY in the CeA, MeA, and BLA structures of NP and P rats. Values represent the mean ± SEM of 4–6 rats in each group. *P < 0.001 versus respective controls.