Carcinoembryonic antigen–related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo
J. Clin. Invest. 116:6 doi:10.1172/JCI24340 [Go to this article.]

Figure 4
Destabilization of endothelial cell networks by anti-CEACAM1 antibodies.

Anti-CEACAM1 antibody AgB10 (0.7 μM) was added to explants of Ceacam1^–/– mice, CEACAM1^endo+ mice, and their appropriate WT littermates for 6 days, and interference with endothelial tube formation is shown. Representative areas of the explants are marked with gray boxes and enlarged correspondingly on the right side of each panel. Magnification, ×100, ×200 (insets).