Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion
J. Clin. Invest. Marie Fischer, et al. 116:2748 doi:10.1172/JCI24274 [
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Figure 7Upregulation of IL-8–positive mast cells in lesional skin from patients with AD or psoriasis. Tissue sections from (
A) psoriatic healthy-looking and (
C) lesional skin were first enzyme-histochemically stained for tryptase. After photography, sections were restained with a polyclonal antibody to IL-8. Results for (
B) psoriatic healthy-looking and (
D) lesional skin are shown. Percentages of IL-8–expressing mast cells in healthy-looking and lesional skin were determined for (
E) 6 AD subjects and (
F) 6 psoriatic subjects. Magnification, ×66.