The AML1-ETO fusion gene and the
FLT3 length mutation collaborate
in inducing acute leukemia in mice
J. Clin. Invest. Christina Schessl, et al. 115:2159 doi:10.1172/JCI24225 [
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Figure 5Histological analyses of leukemic mice. (
A–
F) Histological analyses of AML (mouse no. 14). Original magnifications:
A–
C, ×200; inset in
C, ×1,000;
D and right side of
E, ×250; inset in
D, ×650; left side of
E, ×400;
F, ×400. (
G–
O) Histological analyses of AML with a dominant mast cell population (mouse no. 16). (
G–
L) Primary recipient. (
M–
O) Secondary recipient. Original magnifications:
G and
M, ×100;
H,
J, and
N, ×200;
I,
K, and
O, ×400;
L, ×600. Mast cells with metachromatic granulation in the Giemsa stain are indicated by an arrow. MPO, myeloperoxidase; CAE,
N-acetyl-chloroacetate esterase.