TB, or not TB: that is the question – does TLR signaling hold the answer?
J. Clin. Invest. Terence M. Doherty, et al. 114:1699 doi:10.1172/JCI23867 [
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Figure 3Multifaceted immune responses to MTB. Professional APCs such as macrophages and DCs mount a multifaceted response to pathogen invasion that most often contains or eliminates MTB, but MyD88-dependent innate immune mechanisms appear to be critical to accomplish this task.