The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis
J. Clin. Invest. Armin Schneider, et al. 115:2083 doi:10.1172/JCI23559 [
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Figure 4The G-CSF receptor and its ligand colocalize in neurons in the cortex. Double-immunofluorescence detected G-CSF receptor (G-CSFR) (
A) and G-CSF itself (
B) in identical layer V neurons in the frontal cortex. Note the relatively stronger presence of the receptor in dendritic processes (
C).