Do DNA sequence variants in ABCA1 contribute to HDL cholesterol levels in the general population?
J. Clin. Invest. Päivi Pajukanta, et al. 114:1244 doi:10.1172/JCI23466 [Go to this article.]

Figure 2
The strategy used by Frikke-Schmidt and colleagues (19) to investigate whether DNA sequence variants in the ABCA1 gene contribute to plasma HDL-C levels in the general population. Any variant that causes a premature stop-codon in synthesis of protein is called a nonsense variant.