An integrated view of suppressor T cell subsets in immunoregulation
J. Clin. Invest. Hong Jiang, et al. 114:1198 doi:10.1172/JCI23411 [Go to this article.]

Figure 1
Homeostatic control of the outgrowth of antigen-activated CD4⁺ T cells. Control of the peripheral immunity is accomplished by mechanisms intrinsic to antigen activation of CD4⁺ T cells; including apoptosis, induction of anergy, and differentiation into Th subsets that are independent of other types of regulatory cells. In addition, superimposed on these intrinsic mechanisms are control mechanisms mediated by distinct subsets of NKT, CD4⁺, and CD8⁺ regulatory (suppressor) T cells.