Induction of prolonged survival of CD4+
T lymphocytes by intermittent IL-2 therapy
in HIV-infected patients
J. Clin. Invest. Joseph A. Kovacs, et al. 115:2139 doi:10.1172/JCI23196 [
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Figure 1CD4 and CD8 counts over time for 4 responders to intermittent IL-2 therapy who also participated in labeling studies. The blue lines indicate CD4 cell counts and the red lines indicate CD8 cell counts. The black lines indicate the baseline CD4 counts (mean of 3 values) immediately before the start of IL-2 therapy. Triangles represent individual 5-day IL-2 cycles (3 million to 18 million IU/d). Arrows indicate the IL-2 cycle during which labeling with
2H-glucose (
2H) or BrdU was performed.
