Published in Volume
115, Issue 5 (May 2, 2005)
J Clin Invest. 2005;115(5):1388–1388.
doi:10.1172/JCI23187C1.
Copyright ©
2005, The American Society for
Clinical Investigation.
Corrigendum
Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of
metabolism
Cullen M. Taniguchi, Kohjiro Ueki and C. Ronald Kahn
Published May 2, 2005
Original citation: J. Clin. Invest.
115:718–727 (2005). doi:10.1172/JCI23187
Citation for this corrigendum: J. Clin. Invest.
115:1388 (2005). doi:10.1172/JCI23187C1
Due to an error in manuscript preparation, an incorrect shRNA sequence for IRS2 was
published. The correct hairpin sequence is a 19-nt stretch beginning from nt 703 of the
published IRS2 cDNA sequence (XM_357863). The oligonucleotides cloned into
the U6 construct for the IRS2U6 adenovirus are as follows:
tcgagGTGACGCTGCAGCTTATGAttcaagagaTCATAAGCTGCAGCGTCACttttt (forward) and
ctagAAAAAGTGACGCTGCAGCTTATGAtctcttgaaTCATAAGCTGCAGCGTCACc (reverse). In addition, the
shRNA cassettes were cloned into the adenoviral cosmid pAxcwit, which lacks a promoter,
and not the cosmid pAxCAwtit, as published.
The authors regret this error.
