Natural population dynamics and expansion of pathogenic clones of Staphylococcus aureus
J. Clin. Invest. Damian C. Melles, et al. 114:1732 doi:10.1172/JCI23083 [
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Figure 12D hierarchical clustering of the 1,056
S. aureus strains. The green/red figure represents 155,232 binary outcomes generated by ht-AFLP with 147 marker fragments. Marker absence corresponds with green and marker presence with red. The dendrogram on the
y axis represents the phylogenetic clustering of the 1,056 strains. The dendrogram on the
x axis shows the clustering of the 147 AFLP markers, many of which segregate in specific groups. These groups are cluster specific, and some of these groups are shown as boxes in the figure (A through G). The colored, striped bars on the right represent the distribution of the invasive strains (children and elderly adults), the impetigo isolates, the MRSA strains, and the reference strains. The carriage strains (
n = 829) are not pointed out separately. In conjunction with PCA 3 major (I, II, III) and 2 minor (IVa, IVb) branches were identified; these are represented by the black and white bar on the right of the figure.
