Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy
J. Clin. Invest. Mimoun Azzouz, et al. 114:1726 doi:10.1172/JCI22922 [
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Figure 5Immune response in SMA mice 1 week after intramuscular lentivector-SMN delivery. Abs used to detect components of the immune response in the injected area of muscle were (
A) P7/7: MHC class II; (
B) CD3: T cells; and (
C) FA11: macrophage. All animals exhibited a minor infiltration at site of injections (arrows). Scale bars: 100 μm.