Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation
J. Clin. Invest. Saori Nishio, et al. 115:910 doi:10.1172/JCI22850 [Go to this article.]

Figure 8
Outgrowing Pkd1^–/– MEFs. (A) The 3T3-type culture of MEFs from Pkd1^–/– and wild-type mice. (B) Signaling pathways related to proliferation or apoptosis in Pkd1^–/– MEFs. Expression of signal transducers and cell cycle regulators was analyzed using Western blot. Actin was used as a loading control for protein. Data presented are 1 representative of 4 independent experiments.