Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS
J. Clin. Invest. Luisa M. Villar, et al. 115:187 doi:10.1172/JCI22833 [
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Figure 6Probability of remaining free of IFN-β treatment during follow-up. It was lower in the 15 patients with CSF-restricted LS-OCMBs (LS-OCMB+) than in the 33 patients without LS-OCMBs (LS-OCMB–) (
P < 0.0001).