Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS
J. Clin. Invest. Luisa M. Villar, et al. 115:187
doi:10.1172/JCI22833 [Go to this article.]

Figure 6
Probability of remaining free of IFN-β treatment during follow-up. It was lower in the 15 patients with CSF-restricted LS-OCMBs (LS-OCMB+) than in the 33 patients without LS-OCMBs (LS-OCMB–) (P < 0.0001).