T cell–dependent production of IFN-γ by NK cells in response to influenza A virus
J. Clin. Invest. Xiao-Song He, et al. 114:1812 doi:10.1172/JCI22797 [
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Figure 9The helper function of T cells for fluA-induced IFN-γ production in NK cells can be replaced by exogenous IL-2. PBMCs or CD3-depleted PBMCs from 3 donors (nos. 17–19) were incubated with fluA or control for 17 hours, with or without addition of recombinant IL-2 (250 U/ml). Displayed in the graphs are frequencies of IFN-γ
+ cells in the CD56
bright or CD56
dim NK cell subsets under each condition.
