T cell–dependent production of IFN-γ by NK cells in response to influenza A virus
J. Clin. Invest. Xiao-Song He, et al. 114:1812 doi:10.1172/JCI22797 [Go to this article.]

Figure 8
Suppression of IFN-γ production of NK cells in response to fluA by IL-2–neutralizing Ab. PBMCs from 6 donors (nos. 11–16) were incubated with fluA for 17 hours in the presence of anti–IL-2 Ab or its isotype control (4 μg/ml), respectively, followed by intracellular staining for IFN-γ to determine frequencies of IFN-γ⁺ CD3^–CD56⁺ NK cells. Displayed in the bar graph is the percentage suppression for each donor, which is defined as [1 – (frequency of IFN-γ⁺ NK cells in the presence of anti–IL-2)/(frequency of IFN-γ⁺ NK cells in the presence of isotype control)] ×100.