T cell–dependent production of IFN-γ by NK cells in response to influenza A virus
J. Clin. Invest. Xiao-Song He, et al. 114:1812 doi:10.1172/JCI22797 [Go to this article.]

Figure 6
Level of IFN-γ response of the NK cell subsets correlates with frequency of fluA-specific T cells in PBMCs of 25 donors. PBMCs were incubated with fluA for 17 hours, followed by cytokine flow-cytometric analysis to determine the percentage of IFN-γ⁺ cells in the CD56^bright perforin⁺ NK subset (labeled as CD56^bright), CD56^dim perforin^– NK subset (labeled as CD56^dim), and CD3⁺ T cell subset of each donor. The percentage of IFN-γ⁺ cells in each NK subset was plotted against that in the T cell population from the same donor, respectively. The estimated Spearman correlation coefficient r_S and P value is reported in each plot.