Staphylococcus aureus Panton-Valentine leukocidin directly targets mitochondria and induces Bax-independent apoptosis
of human neutrophils
J. Clin. Invest. Anne-Laure Genestier, et al. 115:3117 doi:10.1172/JCI22684 [
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Figure 8Detection of LukS-PV and of DNA-fragmented cells in lung sections of patients who died from necrotizing pneumonia. (
A) Sections were stained with anti–LukS-PV 1C12 mAb. Arrows indicate LukS-PV–positive cells. (
B) Serial sections were stained by the TUNEL method to detect DNA fragmentation.
