Adenosine and ATP: traffic regulators in the kidney
J. Clin. Invest. Wilhelm Kriz, et al. 114:611 doi:10.1172/JCI22669 [
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Figure 1Structural organization of the nephron. Blood vessels are shown in red; the glomerulus and the tubular system in gray. The afferent arteriole feeds the glomerular capillary network, where filtration of the blood occurs. The glomerular filtrate is processed as it travels through the different tubular segments. At the cell plaque of the MD, with which the TAL touches the vascular pole of its glomerulus, tubular fluid composition is sensed and paracrine signals are conveyed to smooth muscle and renin-producing cells of the afferent arteriole.