Ca_V2.3 calcium channels control second-phase insulin release
J. Clin. Invest. Xingjun Jing, et al. 115:146 doi:10.1172/JCI22518 [Go to this article.]

Figure 5
Confocal immunocytochemistry of insulin and glucagon immunoreactivity in single islet cells. (A) Insulin and glucagon immunoreactivity in dispersed WT islet cells visualized by confocal microscopy. (B) Insulin and glucagon immunoreactivity was visualized as in A, but cells are from CaV2.3^–/– islets. (C) Relative distribution of insulin, glucagon, and double immunoreactivity (Ins⁺, Glu⁺, and Ins&glu⁺, respectively) in WT CaV2.3^+/+ (black bars) and CaV2.3^–/– (gray bars) islet cells. Data represent more than 200 cells in each group and are from 3 different experiments.