Age-dependent incidence, time course, and consequences of thymic renewal in adults
J. Clin. Invest. Frances T. Hakim, et al. 115:930 doi:10.1172/JCI22492 [
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Figure 1TI scale utilized to assess thymic enlargement in thoracic CT scans, based on McCune (
28): 0, no soft tissue with thymus entirely replaced by fat (top left panel); 1, minimal soft tissue, barely recognizable (top right panel); 2, minimal soft tissue more obvious (typical thymus of a middle-aged adult; bottom left panel); 3, moderate soft tissue (bottom right panel). No cases of McCune’s level 4 (moderate soft tissue of greater extent, almost mass-like) or level 5 (mass-like appearance of concern for hyperplasia or thymoma) were observed in these patients.