Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell–driven B cell responses
J. Clin. Invest. Hyung W. Lim, et al. 114:1640 doi:10.1172/JCI22325 [Go to this article.]

Figure 3
Differential expression of chemokine receptors by CD4⁺CD25⁺CD69^– Tregs and CD4⁺CD25⁺CD69⁺ T cells. Fresh tonsil mononuclear cells were stained with antibodies to the indicated chemokine receptors and CD4, CD25, and CD69. (A) Representative dot plot data. (B) Averages and SEM of the data obtained from 3 independent experiments. *Significant differences between the 2 T cell subsets. The P values were 0.03 (CCR2), 0.007 (CCR4), 0.001 (CCR5), 0.039 (CCR6), 0.032 (CCR7), 0.001 (CXCR3), 0.002 (CXCR4), 0.001 (CXCR5), and 0.018 (CXCR6). Mean fluorescent intensity (MFI) levels for the chemokine receptors are also shown in parentheses in B. mIgG2b, mouse IgG2b.