Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone
J. Clin. Invest. Leanne Wilson-Fritch, et al. 114:1281 doi:10.1172/JCI21752 [Go to this article.]

Figure 2
Immunofluorescence analysis of mitochondrial Hsp70. Adipocytes were isolated from the epididymal fat pads of 26-week-old C57BL/6J, ob/ob, and rosiglitazone-treated ob/ob (ob/ob + Rosi) mice. Adipocytes were fixed and stained and image stacks were obtained with a conventional wide-field microscope fitted with a 40× or 100× Nikon plan-apo objective. Images represent single optical sections. White arrows indicate small, droplet-like structures seen only in rosiglitazone-treated cells.