Src promotes estrogen-dependent estrogen receptor α proteolysis in human breast cancer
J. Clin. Invest. Isabel Chu, et al. 117:2205 doi:10.1172/JCI21739 [Go to this article.]

Figure 1
ERα^– and ERα⁺ human breast cancers express ESR1 mRNA. (A) PCR of ESR1 and human PBGD from breast tumors. Blots are representative of 50 ERα⁺ and 200 ERα^– cancers. Con, control. (B) ESR1 mRNA concentrations. The horizontal line denotes the mean. (C) Frequency of ESR1 mRNA concentrations rounded to the nearest logarithm value. (D and E) ESR1 mRNA (fmol/μg total RNA) plotted versus ERα protein by LBA (fmol/μg cytosolic protein) in the same human breast cancers.