EVI1 induces myelodysplastic syndrome in mice
J. Clin. Invest. Silvia Buonamici, et al. 114:713 doi:10.1172/JCI21716 [
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Figure 4EVI1 represses the expression of
EpoR and
c-Mpl. Real-time quantification of
EpoR (squares) and
c-Mpl (circles) normalized to
Gapdh shows a significant decrease of these genes’ median expression in the BM of EVI1-positive mice 4 months after BMT or at the time of their disease-induced death. The results are plotted as the ratio between
EpoR or
c-Mpl and
Gapdh multiplied by 100.
