Peter Billings
J Clin Invest.
2004;
113(8):1114–1117
doi:10.1172/JCI21632
This article Copyright © 2004, The American Society for Clinical Investigation
Abstract
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U
nderstanding of autoimmune sensorineural hearing loss (ASNHL) has been hindered by the inaccessibility of the inner ear to biopsy and the lack of workable animal models. A report in this issue of the JCI describes a mouse model of CD4+ T cell–mediated ASNHL induced by immunization with peptides from the inner ear–specific proteins cochlin and β-tectorin.
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