Increased oxidative stress in obesity and its impact on metabolic syndrome
J. Clin. Invest. Shigetada Furukawa, et al. 114:1752 doi:10.1172/JCI21625 [
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Figure 2Increased oxidative stress in plasma and WAT of obese KKAy mice. (
A) Body weight, parametrial WAT weight, plasma levels of glucose, lipid peroxidation (TBARS), and H
2O
2 in C57BL/6 and KKAy mice at 7 and 13 weeks of age. Values are expressed as mean ± SEM (
n = 6–8). (
B) Tissue levels of lipid peroxidation in WAT, liver, and skeletal muscle of C57BL/6 and KKAy mice. Values are expressed as mean ± SEM (
n = 6–8). (
C) The release of H
2O
2 from WAT, skeletal muscle, and aorta of C57BL/6 and KKAy mice at 7 weeks of age. Values are expressed as mean ± SEM (
n = 5). ***
P < 0.001 compared with C57BL/6 mice.