Salt handling and hypertension
J. Clin. Invest. Kevin M. O’Shaughnessy, et al. 113:1075 doi:10.1172/JCI21560 [
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Figure 2BP changes in chimpanzees fed a salt-supplemented diet. Twenty-two chimpanzees were fed infant formula either alone (
n = 12) or with added salt (
n = 10) as follows: 5 g/d for 19 weeks, 10 g/d for 3 weeks, and 15 g/d for 67 weeks. A 20-week period without added dietary salt concluded the experiment. The BP changes were significantly increased over base line (*
P < 0.05, **
P < 0.01, ***
P < 0.001) and significantly different between groups (
+P < 0.05;
+++P < 0.001). Reproduced with permission from
Nature Medicine (
48).